College of Medicine and Health Sceinces

URI for this communityhttps://rps.wku.edu.et/handle/123456789/45764

College of Medicine and Health Sceinces

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Start date: 2021Subject: search.filters.subject.Central Ethiopia

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    SPECTRUM OF CARDIOVASCULAR DISEASE ADMISSIONS, OUTCOME, AND ASSOCIATED FACTORS IN WOLKITE UNIVERSITY COMPREHENSIVE SPECIALIZED HOSPITAL, CENTRAL ETHIOPIA: RETROSPECTIVE STUDY
    (wolkite University, 2026-06) Dr. Tarekegn Murezha
    Background: Cardiovascular diseases are the leading cause of death globally, with approximately 80% of these deaths occurring in low- and middle-income countries, including Ethiopia. Despite this growing burden, there is a significant lack of localized data on the clinical profile, outcomes, and associated factors of cardiovascular disease admissions in many regions of the country, including the study area. This study seeks to fill that gap by providing crucial evidence from a tertiary care setting. Objective: To assess the clinical spectrum, admission outcomes, and determinants among patients admitted with cardiovascular diseases at Wolkite University Comprehensive Specialized Hospital. Methods: An institution-based retrospective cross-sectional study was conducted among 357 cardiac patients admitted to Wolkite University Comprehensive Specialized Hospital from September 1, 2022, to September 1, 2025. A systematic random sampling method was applied, and all eligible medical records were reviewed from this period. Data on types of cardiovascular diseases, clinical presentation, diagnostic results (including echocardiography), treatment, and inhospital outcomes were collected using a pre-tested, structured data extraction checklist. Data were entered into Epi-Data version 4.6 and then exported to SPSS version 27 for statistical analysis. Descriptive statistics (frequencies, percentages, means, and standard deviations were used to summarize the burden and spectrum of cardiovascular disease. Bivariate analyses and multivariable logistic regression were used to identify factors associated with admission outcomes. A p-value of less than 0.05 at 95% CI was considered statistically significant. Results: A total of 357 cardiovascular disease admissions were included in the analysis. The most common cardiovascular diagnoses were Stroke, heart failure, and ischemic heart disease. The overall in-hospital mortality rate was 10.9%. Among the independent factors, hemorrhagic stroke (AOR = 7.92, P = 0.004) and ICU admissions (AOR =5.45, P = 0.020) are associated with unfavorable outcomes. Conclusion: The study area has a high prevalence of cardiovascular diseases, which significantly increases morbidity and mortality. Overall, this study demonstrates an increasing burden of stroke and heart failure among patients admitted for cardiovascular disease in Gurage zone. The majority of cardiovascular diseases involve potentially modifiable risk factors that may have stopped or slowed the disease’s progression. Among the independent variables hemorrhagic stroke and ICU admissions were associated with poor admission outcome.
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    SELF-MEDICATION PRACTICE AND ASSOCIATED FACTORS AMONG PREGNANT WOMEN IN RURAL KEBELES OF CHEHAWEREDA GURAGE ZONE CENTERAL ETHIOPIA
    (WOLKITE UNIVERSITY, 2024-10-01) SHIKURIA ABDELA
    Introduction: Self-medication practice is the use of drugs without a medical advice to treat selfidentified illnesses. This could lead to a multiple health problems for the mother and the fetus during pregnancy. However, the prevalence is reported to be high both in developed and developing countries. A large proportion of pregnant women in Ethiopia live in rural areas with low healthcare coverage and a lack of basic drug safety information. Despite this, studies are limited in rural Ethiopia and at the community level, and as a result, limited scientific evidence on SMP during pregnancy in the Gurage zone. Objective: To assess the prevalence of self-medication practice and identify its associated factors among pregnant women in rural Keble of Cheha Woreda Method: A community-based cross-sectional study design supplemented with qualitative data was employed on 607 pregnant women and 40 key informants in the rural kebele of Cheha woreda from March 1 to April 30/2024 GC. A multi-stage sampling technique was used to select study participants; the quantitative data was collected using a structured interview questionnaire and analyzed with Binary logistic regression and thematic analysis for qualitative data. Results: Out of the sample pregnant women, 555 pregnant women and 38 key informants participated in the study with a response rate of 91.5%. The overall prevalence of SMP among pregnant women was 286(51.5%).Age of the pregnant women(AOR = 0.34, 95% CI (0.04-3.013)), ANC follow up (AOR=2.94, 95%CI (1.08-8.0)), Pregnancy related problem (AOR =0.056, 95% CI (0.03-0.09)), Knowledge(AOR = 2.02, 95% CI (1.06-3.84)), Distance from health facility (AOR =3.52 95% CI (1.13-10.9)) and Drug availability in the nearest health facility (AOR=2.6,95% CI: (1.44-4.7)) were significantly associated with self-medication practice. Minor illness, low cost alternative and time saving were the reasons to SMP. Conclusion and Recommendation: Almost half of the pregnant women practiced self-medication in the study setting. An awareness-building campaign and health education for pregnant mothers and general population, focusing on rural areas, need to be advocated.
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    SELF-MEDICATION PRACTICE AND ASSOCIATED FACTORS AMONG PREGNANT WOMEN IN RURAL KEBELES OF CHEHAWEREDA GURAGE ZONE CENTERAL ETHIOPIA
    (WOLKITE UNIVERSITY, 2024-04) -SHIKURIA ABDELA
    Introduction: Self-medication practice is the use of drugs without a medical advice to treat self identified illnesses. This could lead to a multiple health problems for the mother and the fetus during pregnancy. However, the prevalence is reported to be high both in developed and developing countries. A large proportion of pregnant women in Ethiopia live in rural areas with low healthcare coverage and a lack of basic drug safety information. Despite this, studies are limited in rural Ethiopia and at the community level, and as a result, limited scientific evidence on SMP during pregnancy in the Gurage zone. Objective: To assess the prevalence of self-medication practice and identify its associated factors among pregnant women in rural Keble of Cheha Woreda Method: A community-based cross-sectional study design supplemented with qualitative data was employed on 607 pregnant women and 40 key informants in the rural kebele of Cheha woreda from March 1 to April 30/2024 GC. A multi-stage sampling technique was used to select study participants; the quantitative data was collected using a structured interview questionnaire and analyzed with Binary logistic regression and thematic analysis for qualitative data. Results: Out of the sample pregnant women, 555 pregnant women and 38 key informants participated in the study with a response rate of 91.5%. The overall prevalence of SMP among pregnant women was 286(51.5%).Age of the pregnant women(AOR = 0.34, 95% CI (0.04-3.013)), ANC follow up (AOR=2.94, 95%CI (1.08-8.0)), Pregnancy related problem (AOR =0.056, 95% CI (0.03-0.09)), Knowledge(AOR = 2.02, 95% CI (1.06-3.84)), Distance from health facility (AOR =3.52 95% CI (1.13-10.9)) and Drug availability in the nearest health facility (AOR=2.6,95% CI: (1.44-4.7)) were significantly associated with self-medication practice. Minor illness, low cost alternative and time saving were the reasons to SMP. Conclusion and Recommendation: Almost half of the pregnant women practiced self-medication in the study setting. An awareness-building campaign and health education for pregnant mothers and general population, focusing on rural areas, need to be advocated.