THE EMERGENICE OF COVID -19 PANDEMIC IN THREATENING THE WORLD IN THE 21 CENTURY

Abstract

The COVID-19 pandemic is considered as the most crucial global health calamity of the century and the greatest challenge that the humankind faced since the 2nd World War. In December2019, a new infectious respiratory disease emerged in Wuhan, Hubei province, China and was named by the World Health Organization as COVID-19 (coronavirus disease 2019. For transmission from animals to humans, direct contact with the intermediary host might be one Route. According to the report of the World Health Organization (WHO as of April 18 2020), the current outbreak of COVID-19, has affected over 2164111 people and killed more than 146,198 people in more than 200 countries throughout the world. Till now there is no report of any clinically approved antiviral drugs or vaccines that are effective against COVID-19. The coronavirus outbreak is severely disrupting the global economy. Almost all the nations are struggling to slow down the transmission of the disease by testing & treating patients, quarantining suspected persons through contact tracing, restricting large gatherings, maintaining complete or partial lock down etc. In this review,We focus on our current understanding of the epidemiology, pathogenesis, Immune response of COVID-19, as well as working mechanism of virus.also describes the emergence of COVID-19 threatening on society, healthy and the possible ways in which the disease can be controlled.