ASSESSMENT OF ANTI TB DRUG NON ADHERENCE AND ASSOCIATED FACTOR AMONG TB PATIENT ATTENDING TB CLINIC IN GURAGE ZONE GOVERNMENTAL HOSPITAL ETHIOPIA

Abstract

Background: Tuberculosis is an infectious diseases caused by bacillus mycobacterium tuberculosis. It typically affect the lung (pulmonary TB). But can also affect other site (extra pulmonary TB).The best estimate is that where 1.4 million tuberculosis death in 2017 and it was one the top 10 case of death Worldwide. According to recent estimate Ethiopia stands 7th in list of high TB burden countries. Non-adherence to ant-TB treatment may result in the emergency of multi-drug resistance (MDR) TB, prolonged infectious and poor tuberculosis treatment outcome. Objective: The objective of this study was to assess anti-TB drug non- adherence and it is associated factor among TB patient in Gurage Zone Governmental Hospital. Methods: Institutional based cross sectional study design was conducted to March 08 to March 25, 2022. was employed to select the study subjects. A total 281 TB patient were participated in the study. Data were conducted using semi-structured questionnaire with morisky medication adherence scale (MMAS). Data were entered and cleaned using statistical package for social science SPSS multiple logistic regression were fitted to identify all action and control potential confounding variable. Adjusted odd ratio with 95% confidence interval was calculated and P value < 0.05 where considered statistically significant. Results: A total 281 Tuberculosis patients were interviewed with response rate of 97.6% were male 144(44.4%) and 129(39.8) were Gurage by Ethnicity. The overall no-adherence was 33(11.8). Non-adherence was prolonged waiting time of get medical science (AOR =1.904, 1.768-4.721) taking beside TB medication (AOR =2.592, 1.189-5.648); inform family and you your friends on TB treatment (AOR = 0.919, 1.316-2.673) and HIV status (4.355, 1.606-11.811)