Browsing by Author "DR. MELKAMU MERDASSA"

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    SURGICAL TREATMENT OUTCOME OF PERFORATED PEPTIC ULCER DISEASE AND ASSOCIATED FACTORS AMONG SURGICALLY TREATED PATIENTS AT WOLKITE UNIVERSITY COMPREHNSIVE SPECIALIZED HOSPITAL RETROSPECTIVE STUDY (SEPTEMBER2019-AUGEST2025)
    (wolkite University, 2026-06) DR. MELKAMU MERDASSA
    Background Peptic ulcer perforation is a surgical emergency and life-threatening complication affecting 2– 10% of peptic ulcer disease patients. Delayed diagnosis and surgical management are associated with significant morbidity and mortality. This study assessed the outcome of Perforated peptic ulcer disease among patients operated at Wolkite university comprehensive specialized hospital, Ethiopia. Objective To study surgical treatment Outcome of Perforated Peptic ulcer disease Patients who underwent emergency Surgical Operations in Wolkite university comprehensive specialized hospital between September 12/2019 to august 2025. Method A six-year hospital based retrospective study, in Wolkite university comprehensive specialized hospital, Wolkite, Ethiopia from September 12/2019 to august 2025 was conducted on 113 patients. Data was entered into EPI data then transferred and analyzed using SPSS windows program version 27. Odds ratio and 95% CI was calculated using the chisquare test and P < 0.05 was considered statistically significant Results Out of 134 cases operated for Perforated peptic ulcer in the study period, charts of 113 cases were analyzed making the retrieval rate 84%. 85%% were males & 51% are above 40 years of age. Previous history of Peptic ulcer disease & cigarette smoking was documented in 54.9% & 8.5% respectively. The post-operative complication rate was 21.1% & overall mortality of the study is 8.9%. Factors found to be significantly associated with increased complications were age above 40 (p=0.002) & treatment delay > 24 hours (p=0.01). Whereas mortality was increased by treatment delay (p=0.04) & shock at presentation (p=0.039). Conclusion and recommendations Perforated peptic ulcers as we have noted from our study is a disease of the young & males like the figures from the developing nations. Perforated peptic ulcer has high rates of overall morbidity & mortality. Early presentation of patients to surgical care facilities may reduce the overall morbidity and mortality