DR. MEBRATU ALAMIREW2026-05-152026-06https://rps.wku.edu.et/handle/123456789/46886Background: Intestinal stoma reversal is performed to restore bowel continuity and improve quality of life. However, it carries substantial morbidity and mortality. Reported morbidity ranges from 10% to 52.1%, and mortality may reach 10%. Despite these risks, local evidence regarding postoperative outcomes and associated factors in Central Ethiopia remains limited. Objectives: To assess postoperative outcome of stoma reversal and identify associated factors among adult patients who underwent stoma reversal in selected hospitals in Central Ethiopia from 2020 to December 2025. Methods: An Institution-based multicenter retrospective cross sectional study was conducted among adult patients who underwent stoma reversal between 2020 and 2025. Data were collected using a structured checklist from medical records, entered into EpiData 4.7, and analyzed using SPSS version 26 for analysis. Binary logistic regression analysis was performed to identify factors associated with postoperative complications. Variables with pvalue < 0.05 in multivariate analysis were considered statistically significant. Results: Of 229 patients who underwent stoma reversal, 185 met the inclusion criteria and were analyzed. Overall postoperative complication rate was 35.1%. Surgical site infection was the most common complication, accounting for 60.9% of all complications. The 30-day postoperative mortality rate was 6.5%. In multivariate analysis, increasing age (AOR=10.8, 95%CI: 2.48-16.68), delayed time to reversal (AOR=6.583 , 95% CI: 1.524-11.282), delayed admiration of prophylaxis (AOR=10.12, 95% CI: 1.82-22.54), the presence of comorbidity (AOR=5.019, 95% CI: 1.076 -23.404) were independently associated with postoperative complications Conclusion: Postoperative complications following stoma reversal remain common, affecting 35.1% of patients. Optimizing perioperative care and timely reversal may help reduce adverse outcomes.enThesis