DR. AKMEL MOHAMED2026-05-152026-06https://rps.wku.edu.et/handle/123456789/46896Background: Asthma is a major health challenge globally where majority of the patients have uncontrolled disease status. According to the Global Initiative for Asthma (GINA) guidelines, one of the goals of asthma management is to achieve clinical control. Despite good understanding of therapeutic regimens, there is evidence for suboptimal asthma control in many patients. However, there is limited local evidence on the magnitude of uncontrolled asthma and its associated factors in our setting. Objectives: The aim of this study is to assess level of poor asthma control and associated factors among asthmatic patients attending public hospitals in Gurage zone, Ethiopia. Methods: An institutional based cross-sectional study was conducted among clinically diagnosed asthmatic patients who were consecutively enrolled from follow up clinic at public hospital in Gurage zone. Data were collected using a interviewer-administered questionnaire and asthma control was assessed based on the Global Initiative for Asthma (GINA) guidelines. Data were entered into Epi-data 4.6 and analyzed using SPSS version 27. Binary logistic regression was used to examine the association between independent factors and uncontrolled asthma. A variables with adjusted odds ratio (AOR) of 0.05 declared as having significant association. Result: Among the 283 study participants, the mean age was 53 ± 14 years, and the median duration of asthma was 9 ± 7 years. Out of total participants,74.9% (212/283) had uncontrolled asthma. Uncontrolled asthma was significantly associated with variables including salbutamol use as rescue medication (AOR = 5.18; 95% CI: 2.21–12.18), poor pMDI technique (AOR = 12.35; 95% CI: 3.54–43.06), presence of comorbid disease (AOR = 3.20; 95% CI: 1.41–7.26), longer asthma duration (>6–30 years) (AOR = 11.3; 95% CI: 6.2–20.6), illiteracy (AOR = 2.51; 95% CI: 1.12–5.62)and lack of regular physician follow-up (AOR 11.65 (2.97– 45.79)) were significantly associated with uncontrolled asthma. Conclusion and recommendation: Nearly three fourth of asthma patient at follow up had uncontrolled asthma. Poor inhaler technique, inadequate follow-up, longer disease duration, comorbid conditions, and lower educational status were factors associated with it. Therefore, promoting regular follow up, strengthening patient centered counseling particularly for patients with comorbidities and low educational status would help control asthmaenAsthmatic patientspoor asthma controlGurage zoneEthiopia.Thesis